北京市2002年预防接种后不良反应分析

Analysis of Adverse Events After Immunization in Beijing in 2002

为评价所使用疫苗的安全性 ,收集了北京市 2 0 0 2年的预防接种后不良反应 (AEFI)资料进行分析。结果显示 :在所使用的 17种生物制品中 ,有 13种出现AEFI,主要发生在小年龄段人群 ,≤ 1岁发生数占总数的 6 4 4 %。在 4 5例AEFI中 ,特异性反应 30例 ,其中 2 8例为Ⅰ型变态反应。目前北京市AEFI发生率维持在较低水平 ,提高疫苗生产工艺和接种人员业务素质 ,对于降低AEFI发生率和维持公众信任非常重要。

In order to assess the sa fety of vaccines used in Beijing,w e collected and analyzed all d ata on adverse events after imm unization (AEFI) in 2002.The result s showed that with 17 vaccines ,13 vaccines occurred adverse events which were mainly among yo unger children,the children ≤1 yea r old accounted for 64.4%.Within total 45 cases,30 were specific reaction,28 were allergy type I.The incidence of AEFI maintains at low er level in Beijing.It is very imp ortant to improve the vaccine prod uction technique and the technical levels of vaccinators for decreasin g the AEFI incidence and maintaini ng public trust.