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肝硬化血锌、透明质酸与肝功能储备

Serum Zinc, Hyaluronic Acid and Hepatic Functional Reserve in Patients with Cirrhosis of Varing Severity
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摘要 测定34例肝硬化,23例正常人血清锌含量,结合透明质酸和肝功能储备Child-Pugh分级评分指标分析,显示肝硬化组血锌明显降低,以B,C级组尤为显著,与正常对照比较,差别具有显著性。透明质酸随肝功能储备下降而明显增高,各组间差别均显著。血锌降低与透明质酸增高呈负相关,与Child-Pugh评分呈负相关。研究结果表明,肝硬化肝功能储备降低伴有锌缺乏,补锌对肝硬化可能有治疗意义。 Serum zinc, as well as hyaluronic acid and the indices of Child-Pugh grading for hepatic functional reserve, was determined in 34 patients with liver cirrho- sis and 23 controls. Compared with that in the controls, serum zinc decreased signifi- cantly in the cirrhosis group, especially in the patients with grade B and grade C. Hyaluronic acid increased significantly with the decrease of hepatic functional reserve in the sequence controls, grade A, B, and C. There was negative correlation between serum zinc and hyaluronic acid, similarly, between serum zinc and scores of Child- Pugh grading. These results show that the decrease of hepatic functional reserve is followed by zinc depletion and zinc supplementation may be of importance in the treat- ment of liver cirrhosis.
出处 《临床消化病杂志》 1993年第3期106-109,共4页 Chinese Journal of Clinical Gastroenterology
关键词 透明质酸 肝功能储备 肝硬变 Cirrhosis Zinc Hyaluronic acid Hepatic functional reserve
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  • 1S. Karayalcin MD,A. Arcasoy Prof MD,O. Uzunalimoglu Prof MD. Zinc plasma levels after oral zinc tolerance test in nonalcoholic cirrhosis[J] 1988,Digestive Diseases and Sciences(9):1096~1102
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