益肾明目方治疗单纯型糖尿病性视网膜病变的临床观察及对红细胞山梨醇含量的影响

Yishenmingmu Formula Used in Simple Diabetic Retinopathy and Its Imprssion on Content of Sorbitol

目的观察中药复方益肾明目方治疗单纯型糖尿病性视网膜病变的临床疗效及其对山梨醇含量的影响。方法将62例糖尿病性视网膜病变患者随机分成治疗组与对照组,治疗组用益肾明目方治疗,对照组用导升明胶囊治疗,疗程均为2个月,于治疗前、后分别进行视力、眼底荧光血管造影检查,以及红细胞内山梨醇、肌醇含量的测定。结果治疗组眼底病变与对照组相比明显减轻,治疗后红细胞内山梨醇含量下降,肌醇含量上升。结论益肾明目方可治疗单纯型糖尿病性视网膜病变,其机理与改善山梨醇代谢有关。

Objective To observe the clinical effect of Yishenmingmu Formula on simple diabetic retinopathy (SDR) and its impression on the content of sorbitol. Method To divide randomly 62 cases of SDR into the treatment group and the control group. The treatment group was given Yishenmingmu Formula for 2 months. The control group was given Daoshengming Capsules. The examinations of vision and cineangiography were taken and the content of sorbitol and myo-inositol in red blood cells were determined before and after the treatment. Result The fundus lesion in the treatment group were obviously asseviated comparing with those in the control group. After the treatment the content of sorbitol was decreased and the content of myo-inositol was increased in the treatment group. Conclusion Yishenmingmu Formula has a certain effect on SDR and can improve the metabolism of sorbitol and myo-inositol.