摘要
ＡＰＩ＿（０１３４）对氧化修饰低密度脂蛋白损伤内皮细胞的影响王宏伟，赵华月，马宝瑕（同济医科大学附属同济医院武汉４３００３０）提要氧化修饰低密度脂蛋白ｏｘＬＤＬ（２．０ｍｇ／ｍｌ）显著增高猪主动脉ＥＣ培养液中的ＥＴ和ＭＤＡ含量，降低ｃＧＭＰ含量和抑制...
rotective effects of API0134 on endothelial cells (EC) damaged by oxidatively modified low density lipoprotein(oxLDL) were studied. The results show, the contens of endothelin (ET) and MDA in the media of EC incubated withoxLDL were increased and the cGMP was decreased significantly, and the activity of SOD was inhibited. The effectof cytotoxicity of oxLDL can be eliminated by API0134. These data sugsest that APl0134 may protect EC against damageselicted by oxLDL.
出处
《中药药理与临床》
CAS
CSCD
1996年第1期27-28,共2页
Pharmacology and Clinics of Chinese Materia Medica
基金
国家自然科学基金
