摘要
背景与目的:临床Ⅰ期非小细胞肺癌是否应常规行纵隔镜检查仍存在争议,本研究旨在评估应用纵隔镜检查临床Ⅰ期非小细胞肺癌纵隔淋巴结转移情况的价值。方法:2000年10月至2004年2月,31例临床诊断为Ⅰ期非小细胞肺癌的患者接受经颈纵隔镜检查。结果:纵隔镜检查共发现2例N2期患者,1例N3期患者(右斜角肌前淋巴结转移),阳性率为10%(3/31);敏感性75%,特异性100%,准确率97%。结论:对临床Ⅰ期非小细胞肺癌进行纵隔镜检查有较大的意义,术前可常规行纵隔镜检查。
BACKGROUND & OBJECTIVE: Whether to apply routine mediastinoscopy to non-small cell lung cancer (NSCLC) of stage Ⅰ remains controversial. This study was to evaluate application of cervical mediastinoscopy in detecting mediastinal lymph nodes status of NSCLC of stage Ⅰ. METHODS: The cervical mediastinoscopy was performed in 31 patients with NSCLC of stage Ⅰ prior to thoracotomy from Oct. 2000 to Feb. 2004. Mediastinoscopy-positive (stage N2) patients received neoadjuvant chemotherapy. RESULTS: Of the 31 patients, 2 had disease of stage N2, and 1 had disease of stage N3 (right scalenus lymph node metastasis);positive rate of mediastinosopy was 10% (3/31), sensitivity, specificity, and accuracy of mediastinoscopy were 75%, 100%, and 97%, respectively. CONCLUSION: Mediastinoscopy might be a routine examination for patients with NSCLC of stage Ⅰ.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
2005年第3期349-352,共4页
Chinese Journal of Cancer
基金
广东省医学科研课题(No.A2002229)~~
关键词
肺肿瘤
纵隔镜检查
新辅助化疗
Lung neoplasms
mediastinoscopy
neoadjuvant chemotherapy
