临床抗感染药物使用的调查分析

Anti-infective Agents Used in Clinics: Investigation and Analysis

目的 提高临床使用抗感染药物的合理性。方法 回顾性调查2003年8月1 007份出院病历使用抗感染药物的情况。结果 抗感染药物使用率73.8%,以二联用药为主;用药指征不明者占 1.6%;抗感染药物收入占药品收入的26.2%;医院感染发病率4.27%,其中真菌感染占17.3%;不良反应发生率为 1.9%。结论 不合理使用抗感染药物可导致疗效不佳、发生医院感染、耐药菌株产生、患者医疗费用上涨以及不良反应的产生,应采取必要的管理措施。

OBJECTIVE To improve rationality of anti infective agents used in clinics. METHODS Antibacterial use of 1 007 cases discharged from hospital in Aug 2003 was retrospectively analyzed. RESULTS The use rate of anti infective agents was 73.8%, in which the drug combination therapy was the majority and the rate of irrational use was 1.6%. The income from anti infective agents occurred 26.2% of total income of hospital. Incidence of nosocomial infection was 4 27%, among them the fungus infection was 17.3%. The rate of adverse reaction was 1.9%. CONCLUSIONS The irrational use of anti infective agents can result in bad therapeutic effect, nosocomial infection, drug fast bacteria, medical treatment fee increase and adverse reaction occurred, so we must adopt management measure.