托品酰胺与阿托品用于少儿弱视验光55例对比

Comparison of topicamide and atropine for optometry in 55 children

目的:对比2种睫状肌麻痹剂在少儿弱视验光中的作用,对托品酰胺在少儿弱视验光中的效果做出判定。方法:需要验光的少儿患者55例(110眼),年龄6～14(9.4±2.4)岁。先用5g/L托品酰胺眼液作睫状肌麻痹验光,发现1眼或双眼矫正视力≤0.8时,再用10g/L阿托品眼液点药3～6d后重验,统计分析2组结果。结果:托品酰胺较阿托品验光结果显著偏近视。配对t检验,两组球镜及等值球镜均有显著差异。球镜偏近视幅度≥0.50D的占50.9%(56/110);等值球镜偏近视幅度≥0.50D的占42.7%(47/110);偏远视的较少,球镜偏远视幅度≥0.50D的占12.7%(14/110),等值球镜偏远视幅度≥0.50D的占10.0%(11/110)。两组柱镜结果,配对t检验无显著差异。最大偏差:偏近视3.25DS,3.25DC,等值球镜2.88D,偏远视1.75DS,2.00DC,等值球镜2.25D。结论:5g/L托品酰胺眼液作为睫状肌麻痹剂用于少儿弱视的验光配镜,不是理想的选择。

AIM: To compare the effect of atropine and tropicamide on children on optomet ry and to evaluate the effect of tropicamide. · METHODS: A total of 55 children (110 eyes) aged 6-14 (9.40±2.35) were select ed. The 5g/L tropicamide was used for cycloplegia firstly. When corrected vision of one or both eyes is ≤0.8, 10g/L atropine was used for cycloplegia after 3-6 d. The results were analyzed by SPSS 10.0 software. · RESULTS: The result of tropicamide was partially more myopic than that of tha t of atropine. The matched-pairs't-test revealed that the two sphere values an d equivalent sphere values were significantly different. The percent of the sphe re more myopic(≥0.50D) is 50.9% (56/110); and the percent of equivalent sphere more myopic(≥0.50D) is 42.7%(47/110). There are relatively fewer results that a re more hyperopic. The percent of the sphere more hyperopic(≥0.50D) is 12.7%(14/110) and the percent of equivalent sphere more hyperopic (≥0.50D) is 10.0%(11/ 110). The results of cylinder are not significantly different. The largest devia tion that is more myopic is 3.25DS and 3.25DC and that is more hyperopic is 1.75 DS and 2.00DC. · CONCLUSION: The 5g/L tropicamide used for optometry in children is not an ide al selection. ·