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穿琥宁与维生素B_6不恰当配伍状态分析 被引量:6

An analysis of inappropriate compatibility of potassium dehydrograpolide succinate and vitamin B_6
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摘要 目的:探讨穿琥宁与维生素B6不恰当配伍情况.方法:用10%葡萄糖分别稀释穿琥宁、维生素B6、阿奇霉素至不同稀释浓度,将稀释后溶液两两混合,用肉眼观察各管结果.结果:0.05%~5%稀释的阿奇霉素与0.05%~5%不同稀释的注射用穿琥宁溶液、1:5~1:80不同稀释的维生素B6溶液混合管未产生浑浊.而0.05%~5%稀释的注射用穿琥宁与1:5~1:80不同稀释的维生素B6溶液混合管均产生乳白色浑浊.结论:穿琥宁与维生素B6存在配伍禁忌. Objective: To report the situation of inappropriate compatibility of potassium dehydrograpolide succinate and vitamin B_6. Methods: Dilution potassium dehydrograpolide succinate, Vitamin B_6 and azithromycin aspartate were diluted with 10% GS separately and then the abovementioned solutions were mixed in pairs, and the results were observed. Results: Turbidity was seen in the mixtures of azithromycin aspartate between 0.05% ~ 5% densities and Vitamin B_6 from 1∶5 to 1∶80 densities; other mixtures are limpid. Conclusions: Potassium dehydrograpolide succinate and vitamin B_6 are of incompatibility.
出处 《儿科药学杂志》 CAS 2005年第1期41-42,共2页 Journal of Pediatric Pharmacy
关键词 穿琥宁 维生素B6 浑浊 配伍禁忌 Potassium dehydrograpolide succinate Vitamin B_6 Turbidity Incompatibility
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  • 1余自成.大环内酯类抗生素的正确选用[J].国外医药(合成药.生化药.制剂分册),1998,19(3):160-163. 被引量:10
  • 2Peters DH, Friedel HA, McTavish D. Azithromycin, a review of its antimicrobial activity, pharmacokinetic properties and clinical efficacy [J]. Drugs, 1992, 44(5): 750.
  • 3Girard AE, Girard D, English AR, et al. Pharmacokinetic and in vivo studies with azithromycin ( CP-62,993 ), a new macrolide with an extended half-life and excellent tissue distribution [J]. Antimicrob Agents Chemother, 1987, 31(12): 1948.

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