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急性肾小球肾炎患儿氧自由基的变化 被引量:3

The Changes of Oxygenmediated Free Radical in Children with Acute Glomerulonephritis
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摘要 本文检测了急性肾小球肾炎患儿血清超氧化物歧化酶(SOD)活力60例与过氧化脂质(LPO)含量28例,并以正常儿童为对照。结果表明,患儿血清SOD活力为24.517±7.369u/ml,较对照组39.66±13.24/ml显著降低;患儿血清LPO含量为1.512±0.841μmol/L,较对照组1.098±0.488μmol/L显著升高。说明氧自由基与本病的发生发展有关,并建议临床应用抗自由基药物治疗。 In this study, the activity of serum superoxide dismutase (SOD) of 60cases and the content of serum lipid peroxide(LPO) of 28 cases with acute glornerulonephritis(AGN) were determined. The results showed that the serum SOD activity in patients was found to be 24. 517±7.369u/ml,being decreased remarkably than 39.66 ± 13.24u/ml in the healthy children, the content of serum LPO in patients was found to be 1.512 ± 0.84/μmol/L, being increased signf-icantly than 1. 098 ± 0. 448μmol/L in the control group. It confimed that oxygenmediated free radical (OFR) was connected with the occurrence and development of AGN. We propose to take the drugs of antagonist OFR for clinical application.
出处 《咸宁医学院学报》 1996年第2期68-69,共2页 Journal of Xianning Medical College
关键词 急性肾小球肾炎 患儿 氧自由基 对照组 临床应用 LPO 血清 歧化 降低 活力 acute glomerulonephritis oxygenmediated free radical superoxide dismu-tase lipid peroxides
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