针刺防治环磷酰胺所致大鼠肝肾功能及脏器损害的作用

Acupuncture Can Prevent Dysfunctions and Destructions of the Liver and Kidney due to Cyclophosphamide in Rats

大鼠腹腔注射环磷酰胺后,其血清谷丙转氨酶、尿素(?)含量均较正常纽显著升高(P<0.01),提示肝、肾功能出现异常变化;同时,动物胸腺、脾、肝、肾、胃及十二指肠等脏器亦发生一系列病理改变。针刺足三里能有效防止和治疗环磷酰胺对大鼠的上述损害,针刺尾部非穴点则无治疗作用,表明按中医理论和经络学说选取穴位诚属至关重要。

The marked increases in serum glutamic pyruvlc transaminase and urea nitrogen obtained after an intraperitoneal injection of cyclophosphamide indicated the dysfunctiors of the liver and the kidney in rats.Following the injection,pathologic changes could alsobe seen in the thymus,spleen,liver,kidneys,sto-mach and duodenum.Acupuncture at Zusanli(ST 36)could effectively prevent and cure the above dysfun-ctions and destructions due to cyclophosphamide in therats,whereas needling caudal non-acupoint loci failedto affect the animals.These results strongly suggestthat it is significant to choose acupoints accordingto the meridian theory of T.C.M.