铜绿假单胞菌耐药性监测结果分析

Analysis on drug resistance of pseudomonas aeruginosa

目的 :了解铜绿假单胞菌医院感染的分布及其耐药性的变化趋势。方法 :对2003年1月～2003年12月分离的铜绿假单胞菌210株进行11种抗生素的药敏实验 ,对铜绿假单胞菌耐药性进行统计分析。结果 :铜绿假单胞菌在临床分离株中列第2位 ;感染部位主要是呼吸道 (188/210 ,89 52 % ) ,和伤口 (12/210 ,5 71 % ) ;丁胺卡那敏感率71 43 % ,亚胺培南为64 29 % ,头孢他啶为57 14 %。结论 :了解铜绿假单胞菌的耐药现状 ,可为临床抗生素治疗提供更多依据。临床医生应根据药敏结果 ,合理应用抗生素对铜绿假单胞菌感染患者进行治疗。

Objective:To investigate the distribution of nomocomial infection and drug resisˉtance of Pseudomonas aeruginosa.Methods:During2003,210strains of Pseudomonas aeruginosa were separated,identified and given drug sensitive tests.Results:Pseudomonas aeruginosa was in the second place in clinical separated strains.89.52%of Pseudomonas aeruginosa was found from sputum(188/210)and5.71%was found from secretion(12/210).Amikacin,imipenem and ceftazidime had stronger activity against Pseudomonas areuginosa with the susceptibility of71.43%,64.29%and57.14%respectively.Conclusion:In order to provide more evidence for clinical therapy,the stains of resistance of Pseudomonas areuginosa should be investiˉgate.Clinical Practioner may choose antibiotics rationally with the Pseudomonas areuginosa-infected patients according to drug-resistance test.