摘要
冠心病心绞痛74例,其中46例(男性32例,女性14例;年龄65±s8a)采用尼卡地平40mg,po,bid为治疗组;另28例(男性15例,女性13例;年龄62±9a)采用丹参舒心胶囊2粒,po,tid为对照组。12wk后,临床与心电图总有效率,治疗组依次为91%和72%,对照组为68%和43%,治疗组优于对照组(P均<0.001)。尼卡地平尚有减慢心率。降低血压及改善左室收缩功能等作用,不良反应轻微。
Forty six patients(M32,F14;age 65±s 8 a)with angina pectoris were treated with nicardipine(40 mg,po,bid×12 WK).The clinical total effective rate was 91%and ECG total effective rate was 72%.Another 28 patients(M 15,F13;age 62±9 a) were treate d with Dan-shen-shu-xing capsule 2 pills(each pill contains Salvia miltiorrhiza 0.2g)po,tid×12 WK.The clinical total effective rates were 68% and 43% respectively.Nicardipine group were superior than Salvia miltiorrhiza group(P<0.001).Nicardipine slowd herat rate,decreaed blood pressure,and improved the svstolic function of left ventricle.Adverse reactions were mild.
出处
《新药与临床》
CSCD
北大核心
1994年第3期169-172,共4页
关键词
尼卡地平
丹参
心绞痛
nicardipine
Salvia miltiorrhiza
angina pectoris