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老年糖尿病患者脂蛋白(a)和纤维蛋白原水平变化的研究 被引量：4

Relationship of the Levels of Lipoprotein(a) and Fibrinogen(Fbg) in Old Diabetic Mellitus
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摘要 目的探讨老年糖尿病患者脂蛋白(a)[Lp(a)]和纤维蛋白原(Fbg)水平变化的临床意义。方法　测定50例老年糖尿病患者和28例糖尿病合并脑梗死患者的Lp(a)和纤维蛋白原(Fbg)含量。结果　糖尿病组及糖尿病合并脑梗死患者较正常组Lp(a)、Fbg显著升高(P<0.05)。结论　糖尿病患者体内存在高凝状态,Fbg和Lp(a)水平升高与糖尿病血管并发症的发生和发展密切相关,易致血栓形成。 Objective To study the relationship between lipoprotein (a) [Lp(a)]and fibrinogen(Fbg)in old diabetic mellitus(DM). Methods The levels of serum Lp(a) ,Fbg were measured in a group of elderly DM and its control. Results The DM groups with and without cerebral infraction had higher values than the control in the following parameters:Lp(a) ,Fbg(P <0.05). Patients with cerebral infraction also had higher values of Lp(a), Fbg(P < 0.05) than the DM groups. Conclusion There are increased coagulation, decreased fibrinolysis activities in the eldly patients with DM,especially with cerebral infraction. Combined with increased Lp(a) ,these may aggravate pathophyssiological process. All these changes have close relationship with the vascular complications of DM and its severity.
作者 黄松音 姚燕丹 段朝晖
机构地区 中山大学附属第二医院检验科 广州医学院第二附属医院外科
出处 《血栓与止血学》 2005年第2期81-82,共2页 Chinese Journal of Thrombosis and Hemostasis
关键词 糖尿病 脂蛋白 纤维蛋白原 Diabetic mellitus Lipoprotein(a) Fibrinogen
分类号 R587.1 [医药卫生—内分泌]
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参考文献6

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共引文献17

同被引文献23

  • 1田清武,周淑华,伦立民.心脑血管疾病及糖尿病与血清脂蛋白(a)的关系[J].齐鲁医学杂志,2005,20(2):115-116. 被引量：1
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  • 3龚建明,黎龙群,余志彬.血脂水平与2型糖尿病伴发大血管病变关系的探讨[J].现代医药卫生,2007,23(8):1201-1202. 被引量：4
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引证文献4

二级引证文献17

血栓与止血学
2005年 第2期

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