肿瘤靶向性腺病毒研究进展
Development of adenovirus in targeting gene therapy to tumor
摘要
腺病毒是目前恶性肿瘤基因治疗中应用最广泛的基因转移载体,但由于其缺乏靶向性而严重限制了其介导基因治疗的临床应用。开发具有肿瘤靶向性的病毒载体是腺病毒载体的发展方向与研究热点,而对腺病毒衣壳进行改造使其能够靶向性感染肿瘤细胞是靶向性腺病毒研究的重点。现综述近年来腺病毒载体的研究进展。
出处
《国外医学(肿瘤学分册)》
2005年第4期243-246,共4页
Foreign Medical Sciences (Cancer Section)
基金
国家863资助项目(2001AA217121)
参考文献28
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