摘要
丹参加温血持续灌注对心肌缺血再灌注损伤心肌能量物质影响的动态观察哈尔滨医科大学病理生理教研室（哈尔滨１５００８６）马丽英，王孝铭，高翠霞，李向青，娄延平哈尔滨医科大学附属第二医院心胸外科夏求明，向桂玉，姚志娄，祁家驹，唐玉蓉，宁晓华摘要本文首次在丹参...
On the experimental basis of ischemia and reperfusion,author adopted retroperfusion of salvia miltiorrnza(SM) plus warm blood cardioplegia to test their protective effect on myocardium.It was for the first time in human valvular-replacement of seven cases of rheumatic heart disease.Compounds associated with energy metabolism of myocardium at various time points of operation were measured by HPLC.The results showed that following valvular-replacement,PCr and ATP content were not much different at three time points (Ⅰ、Ⅱ and Ⅲ).ADP and AMP content was obviously increase,but decrease of NAD was not marked,and TAN was indistinctly changed.Although apparent energy charge showed decreasing tendency,but its rate was slow.In conclusion SM plus warm blood cardioplegia has more satisfactory myocardial protective effect than cold potassium diluted blood in antegrat and retroperfusion.
出处
《中国病理生理杂志》
CSCD
北大核心
1994年第6期587-590,共4页
Chinese Journal of Pathophysiology
