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降血脂新药匹伐他汀 被引量:32

A new lipid-lowering agent:pitavastatin
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摘要 匹伐他汀是新一代他汀类药物。该药不仅具有较强的HMG-CoA还原酶抑制作用,而且呈肝细胞选择性,药动学性质优异,安全性好,已被制药界誉为是“超级他汀”。现就匹伐他汀的药理及临床应用进行综述。 Pitavastatin is the most recently approved statin. It not only competitively inhibits HMG-CoA reductase,but also has liver-selective action, thus being regarded as 'superstatins'. This paper reviews pharmacology and pharmacotherapy of pitavastatin.
出处 《中国新药杂志》 CAS CSCD 北大核心 2005年第4期483-487,共5页 Chinese Journal of New Drugs
关键词 匹伐他汀 HMG—CoA还原酶抑制剂 降血脂 pitavastatin HMG-CoA reductase inhibitor lipid-lowering
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