甲状腺手术中显露喉返神经价值的Meta分析

The evaluation of recurrent laryngeal nerves exposure during thyroid resection:a meta-analysis

目的 评价甲状腺手术中显露喉返神经对预防喉返神经损伤的价值。方法 收集国内多个数据库符合入选标准的19个对照临床研究,采用固定效应模型和随机效应模型对92 6 9例患者中的喉返神经损伤资料进行Meta分析。结果 19个对照临床研究中,显露喉返神经病例的喉返神经损伤率低(OR 0 2 9,95 %CI0 16～0 5 4 ,P <0 0 0 1)。

Objective To evaluate recurrent laryngeal nerves exposure during thyroid resection. Methods Nineteen case-control clinical trials were collected from relevant studies published in different Chinese databases, and 9269 cases were collected for analysis OR (odds ratios). 95% confidence intervals using the Mantel-Haenszel method for a fixed-effects model, and the Mantel-Haenszel method for a random-effects model were summarized. Both fixed effect model and random effect model were applied to analyze the results and heterogeneity. Results The injury rate of the recurrent laryngeal nerves was significantly lower in exposure group ( OR 0.29, 95% CI 0.16～0.54, P <0.001). Conclusion Routine exposure of recurrent laryngeal nerves during thyroid resection reduces the risk of recurrent laryngeal nerve injury.