犬瘟热脏器组织中的抗原定位及病理形态学观察

Localization of Canine Distemper Antigen in organ Tissues and Pathomorphologic Observation

本文采用免疫组化间接ＢＡ法，对临诊疑似犬瘟热病犬脏器组织中的抗原，进行了定位检查并进行了系统病理学观察。结果表明：发病犬大脑、小脑、延髓、肺、心、脾、膀胱、肠、肝、胰、肾上腺等组织细胞及血管内皮、支气管上皮细胞胞浆内均可见抗原阳性反应。同时，抗原阳性反应组织、器官均可见不同程度的病理变化。

The localization of Canine distemper virus(CDV)antigen in the tissues of infected dogs wasdetected by BA method,and the gross anatomy and histopathological changes of infected dogs were observed.The results showed that the antigen positive reaction were observed in the intravascular cells,epithelial cellsof bronchus and parenchymal cells of cerebrum,heart,cerebellum,medullury bulb, lung,spleen, urinarybladder,liver, intestine,pancreas and adrenal grand.Meanwhile,the pathological changes were observed inthese tissues and organs.