摘要
用Michaelis-Becker反应合成了8个烷基膦酸二正己酯;并改进方法,利用相转移催化技术合成了4个高位阻烷基膦酸二正己酯;同时还观察到产物折光率的加和性及随温度变化的规律。
Di-n-hexyl alkylphosphonates were prepared with the Michaelis-Becker reaction.4 highly hindered alkylphosphonates were synthesized by the modified Michaelis-Becker reaction, using 18-crown ether-6 or quaternary ammonium halides as the phase transfer catalyst.The refraction of many alkylphosphonates were determined and their uarying law was also studied.
出处
《中国药物化学杂志》
CAS
CSCD
1994年第1期51-56,共6页
Chinese Journal of Medicinal Chemistry
基金
国家自然科学基金
关键词
烷基膦酸酯
合成
折光率
Alkylphosphonates
Michaelis-Becker reaction
Phase transfer catalysis
A refractive index