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转化生长因子β/Smad信号传导机制及其与肝纤维化的关系 被引量:12

Mechanism of transforming growth factor beta/Smad signaling and the relationship between its transduction and liver fibrosis
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摘要 目前对转化生长因子β(TGF β)/Smad信号传导通路中的分子基础及其调控机制有一定的研究,已知它控制诸多细胞生命过程,如细胞增殖、凋亡、识别、分化等.在肝纤维化形成过程中TGF β/Smad信号传导对肝星状细胞(HSC)的分化、增殖及合成胶原蛋白方面起极其重要作用,现就有关TGF β/Smad信号传导分子机制及其在肝纤维化中的作用综述如下.
作者 李蕴铷 魏来
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2005年第6期476-478,共3页 Chinese Journal of Hepatology
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