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妥泰引起严重认知障碍 被引量:9

Severe cognitive deficit caused by Topiramate
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摘要 目的探讨癫痫患者服用妥泰出现严重认知障碍的特点。方法对3 例服用妥泰后出现严重认知障碍的癫痫患者的临床资料进行总结。结果与结论多表现为语言功能受损,尤其是语言流畅性受损,而严重认知障碍的患者除了上述表现外,还伴有严重记忆力、计算力障碍。 ObjectiveTo investigate the character of severe cognitive deficit caused by topiramate(TPM) administration in epileptic patients.Methods3 epileptic patients who suffered from severe cognitive deficit following topramate treatment were analyzed.Results and ConclusionTheir verbal functions were often affected especially the fluency of speech, as well as their memory and calculation.
出处 《中国康复理论与实践》 CSCD 2005年第5期402-403,共2页 Chinese Journal of Rehabilitation Theory and Practice
关键词 妥泰 癫痫 认知障碍 副作用 Topiramate epilepsy cognitive deficit side effect
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  • 1Biton V. Preliminary open-label experience with topiramate in primary generalized seizures[ J ]. Epilepsia, 1997,38,42 - 48.
  • 2Korean Topiramate Study Group. Topiramate in medically intractable partial epilepsies. Double-blind piacebo-controlled randomized parallel group trial[ J ]. Epilepsia, 1999,40 : 1767 - 1774.
  • 3Joseph F, Goldberg MD, Katherine E, et al. Cognitive side effects of anticovulsants[ J ]. J Clin Psychiatry, 2001,62 : 27 - 33.
  • 4Thompson PT, Baxendale SA, Duncan iS. Effect of topiramate on cognitive function[ J ]. J Neurol Neurosurg Psychiatry, 2000,69 : 636 - 641.
  • 5Privitera M, Fincham R, Penry J, et al. Topiramate placebo controlled dose : ranging trial in refractory partial epilepsy using 600,800, and 1000 mg daily dosages[ J ]. Neurology, 1996,46 : 1678 - 1683.
  • 6Crawford P. An audit of topiramate use in a general neurology clinic [ J ]. Seizure, 1998,7 : 207 - 211.
  • 7Mohamed K,Appleton R,Rosenbloom L. Efficacy and tolerability of topiramate in childhood and adolescent epilepsy : a clinical experience[ J ] . Seizure, 2000,9(2) : 137 - 141.
  • 8Reife R, Pledger G, Wu SC. Topiramate as add-on therapy : pooled analysis of randomized controlled trials in adults [ J ]. Epilepsia,2000.41 : s66 - s71.
  • 9Biton V, Edwards KR, Montouris GD, et al. Topiramate titration and tolerability[ J ]. Ann Harmacother, 2001.35 : 173 - 179.
  • 10Crawford P. An audit of topiramate use in a general neurology clinic[ J ]. Seizure, 1998,7 : 207 - 211.

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