带蒂皮瓣最佳断蒂时间的实验研究

Experimental study on optimal detachment time for pedicle flap

本文报告了带蒂皮瓣最佳断蒂时间的实验研究．选用大白鼠的下腹部皮瓣，以腹壁浅动、静脉为血管蒂．按断蒂时间分为１、２、３、５、７、１０、１４、２１天８个实验组；同时另设三组，在３、７、１４天断蒂前进行皮瓣训练。测量断蒂３周后皮瓣的成活率、弹性及组织学形态。结果表明５天及其以后断蒂者皮瓣成活率及其弹性与正常皮肤无显著差别；断蒂前训练者可提高其成活率和弹性．

Abstract The experimental study on optimal detachment time for pedicle flap were carried on rats. The lower abdomen flap was chosen with the vascular pedicle of superficial epigastric artery and vein. 11 groups were established based on the detachment time at 1, 2, 3, 4, 5, 7, 10, 14,21 days, and pedicle training before detachment at 3. 7, 14, days. The survival rate, elasticity and histological exam mation were recorded three weeks after detachment. The results showed no significant difference between the normal skin and the flap detached at or more than 5 days in the survival rate and elasticity. pedicle training could improve the survival rate and elasticity.