制备海藻酸钠-壳聚糖生物微胶囊的技术研究

A Study on the Preparatory Technique of Alginate/Chitosan Bio-microcapsule

以海藻酸钠和壳聚糖为原料,研究了采用界面络合方法制备藻酸钠-壳聚糖生物微胶囊的技术条件和影响因素。结果表明,在胶珠反应温度为30℃、反应时间为20min、海藻酸钠浓度为2.0%、氯化钙浓度为4.0%、壳聚糖溶液的浓度1.8%、海藻酸钙胶珠与壳聚糖溶液的比例为1∶5、成膜反应时间10min、覆膜时间8min为最佳的微胶囊制备条件。

Taking alginate and chitosan as the raw material, the technology and effects of the preparation of alginate-chitosan(ACA) bio-microcapsule by the interface-complexation method have been studied. The result has shown that when the reaction temperature of the calcium-alginate gel is 30℃,the reaction time is 20 min, the concentration of alginate, calcium-chlorinate and chitosan are 2.0%, 4.0% and 1.8%, the membrane formation time,membrane overlay time and liquefaction time is 10 min,10 min and 8 min, the ACA bio-microcapsule has good preformance.