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肾素-血管紧张素系统与心房颤动心房结构重构研究进展 被引量:14

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摘要 心房颤动(AF)使心房发生结构重构,主要表现为心房肌间质纤维化、肌原纤维溶解和细胞凋亡等,在促进AF发作和持续中发挥重要作用。新近研究发现,AF时心房肌局部肾素血管紧张素系统(RAS)激活是引起心房肌间质纤维化、肌原纤维溶解和细胞凋亡的主要原因之一,与AF心房结构重构关系密切。
作者 李悦 李为民
出处 《中国心脏起搏与心电生理杂志》 2005年第3期232-234,共3页 Chinese Journal of Cardiac Pacing and Electrophysiology
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  • 1Li D, Shinagawa K, Pang L, et al. Effects of angiotensin-converting enzyme inhibition on the development of the atrial fibrillation substrate in dogs with ventricular tachypacing-induced congestive heart failure[J]. Circulation, 2001, 104:2608.
  • 2Goette A, Staack T, Rocken C, et al. Increases expression of extracellular signal-regulated kinase and angiotensin-converting enzyme in human atria during atrial fibrillation[ J]. J Am Coll Cardiol,2000,35 : 1669.
  • 3Li P, Chen PM, Wang SW, et al. Time-dependent expression of chymase and angiotensin converting enzyme in the hamster heart under pressure overload [ J ]. Hypertens Res, 2002,25:757.
  • 4Passier RC, Smits JF, Verluyten MJ, et al. Expression and localization of renin and angiotensinogen in rat heart after myocardial infarction[ J ]. Am J Physiol, 1996 ,271 : H1 040.
  • 5Busatto VC, Cicilini MA, Mill JG. Increased angiotensin-converting enzyme activity in the left ventricle after infarction [ J ].Braz J Med Biol Res, 1997,30:679.
  • 6Xu J, Cui G, Esmailian F, et al. Atrial extracellular matrix remodeling and the maintenance of atrial fibrillation [ J ]. Circulation,2004,109:363.
  • 7Hoit BD, Takeishi Y, Cox M J, et al. Remodeling of the left atrium in pacing-induced atrial cardiomyopathy [ J ]. Mol Cell Biochem,2002 ,238 : 145.
  • 8Berglund H, Boukter S, Theodorsson E, et al. Raised plasma concentrations of atrial natriuretic peptide are independent of left atrial dimensions in patients with chronic atrial fibrillation [ J ]. Br Heart J,1990,64:9.
  • 9Goette A, Hoffmanns P, Enayati W, et al. Effect of electrical cardioversion on serum aldosterone in patients with persistent atrial fibrillation[ J]. Am J Cardiol,2001,88 :906.
  • 10Ausma J, Wijffels M, Thone F, et al. Structural changes of atrial myocardium due to sustained atrial fibrillation in the goat[ J]. Circulation, 1997,96:3157.

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