肾虚痹证(类风湿性关节炎)发病机理研究

Study on Pathogenic Mechanism of Bi-syndrome (Rheumatoid Arthritis) of Deficient-kidney Type,

以Ⅱ型胶原免疫所致关节炎动物模型为基础,以风寒湿为痹证外因,肾虚为痹证内因的学说为依据,利用中西医结合肾本质研究的成果,采用复合因子方法制作痹证病证结合动物模型,探讨了不同方法所致肾虚对痹证发病的影响,并初步观察到这种影响是不相同的。

The experiments were based on animal models of arthritis caused by II collagenous immunity with the theories of wind- damp- cold as its exogenous factor and kidney deficiency as its endogenous factor The animal models of combined type of syndrome and disease were induced by method of complex facotrs based on the study of kidney nature by integrated modality. Exploration was made on the influence of pathogensis in deficient kidney caused by various methods. Preliminary conclusion showed that such influence yielded different results.