摘要
采用电子自旋共振(ESR)方法测定了照射前给予人参多糖3d,对X射线照后小鼠脾脏自由基含量的影响。结果表明,(1)人参多糖可使3GyX射线照射后小鼠脾脏自由基含量明显降低。(2)不同浓度(12、250、500mg·kg-1·d-1)人参多糖对3Gy照射小鼠脾脏自由基含量均有明显的降低作用。(3)人参多糖对3Gy照射后6h小鼠脾脏自由基含量降低最明显。提示,人参多糖可降低中等剂量X射线照射后早期小鼠脾脏中的自由基含量。
The effects of PGS injection before total body X-irradiation on free radicals changes in spleen of mice were studied by means of ESR technique.The results showed that the contents of free radicals in spleen of mice injected with PSG before irradiation were lower than those of irradiation control group at 3Gy.Different concentration of PSG(125~500 mg/kg.d) could markedly decrease the contents of free radicals in irradiation group with 3Gy. While, free radicals in group with PSG 6 h, after irradiation were significantly lower than those irradiation control group. The results indicated that PSG could decrease free radicals in 3Gy X-rays irradiated mice especially for 3 hours after irradiation.
出处
《辐射研究与辐射工艺学报》
CAS
CSCD
北大核心
1995年第4期246-248,共3页
Journal of Radiation Research and Radiation Processing