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钼对汞毒性的保护作用 被引量:5

PROTECTIVE EFFECT OF MOLYBDENUM ON THE TOXICITY OF MERCURY
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摘要 单独给大鼠氯化汞(10.9mg/kg.d×3)投药3天内全部死亡,但预先投以钼酸钠(100mg/kg。d×3)后再给同剂量氯化汞的动物全部存活,后者脑、肾、肝中汞含量比单独给氯化汞的动物减少,而肾、肝中钼含量增加,尿汞日均排出量增加,尿钼日均排出量及脑中钼含量不增加,肝、肾、血清中脂质过氧化物含量钼汞组比汞组明显降低,上述结果表明钼对汞的毒性有保护作用。 Molybdenum may exert effect on the toxicity of mercury chloride. After giving mercury chloride (10.9mg/kg. d×3) alone for three days, all rats died within three days. However, if sodium molybdate (100mg/kg.d×3) was given in advance, rats administered with same dose of mercury chloride all kept alive after three days, In animals of latter group, the mercury level in the brain, kidney and liver lowered, whereas molybdenum level in brain was not high,and more mercury was discharged in urine. The level of lipid peroxide of molybdenum-mercury group was lower than that of mercury group. The result shows that molybdenum might have a potential protective effect on the toxicity of mercury.
作者 连祥霖
出处 《工业卫生与职业病》 CAS CSCD 1995年第3期149-150,共2页 Industrial Health and Occupational Diseases
关键词 微量元素 过氧化脂质 毒性 毒理学 Trace element Lipid peroxide
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同被引文献19

  • 1朱砂,郑波,杨铟,刘毓谷.氯化汞的肝细胞毒性与脂质过氧化[J].同济医科大学学报,1993,22(6):423-426. 被引量:2
  • 2朱士雅,胡蓉芳,顾素斐,李凭建,王兰.氯化汞对大鼠生殖系统及受孕率的影响[J].职业医学,1994,21(2):13-15. 被引量:4
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  • 10连祥霖.锌对汞毒性的拮抗作用[J]卫生毒理学杂志,1992(02).

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