摘要
本文用酶联免疫吸附试验、单向免疫扩散等方法检测了氟暴露工人血清可溶性白细胞介素２受体（ＳＩＬ－２Ｒ），α肿瘤坏死因子（ＴＮＦα）和免疫球蛋白ＩｇＡ、ＩｇＭ、ＩｇＧ。结果显示工人血清ＴＮＦα含量与氟暴露工龄有关，表现为短期氟暴露工人ＴＮＦα增加，而长期氟暴露工人ＴＮＦα降低。ＳＩＬ－２Ｒ及ＩｇＡ、ＩｇＭ、ＩｇＧ含量则两者之间无明显差异。提示氟对暴露工人免疫功能的影响呈双向性。
The contents of serum soluble interleukin 2 receptor (SIL-2R),tumor necrosis factor α(TNFα)and IgA, IgM,IgG were measured by ELISA or radio-immunodiffusion technique in fluoride ex posed workers. The results showed that level of serum TNFα was significantly increased in group A and apparently decreased in group B. There were no differences in contents of SIL-2R and IgA,IgM, IgG among three groups. It is suggested that the influence of fluoride on immune function could possess two-way action.
出处
《工业卫生与职业病》
CAS
CSCD
1995年第5期280-281,共2页
Industrial Health and Occupational Diseases
