摘要
测定了３５例低肾素性老年高血压病患者降压治疗前后血浆精氨酸加压素（ＡＶＰ）和血清尿酸浓度的改变，并与３０例正常人作对照。结果表明：①患者ＡＶＰ浓度显著增高（Ｐ＜０．０１），且与血压呈正相关。②患者血清尿酸浓度高于正常（Ｐ＜０．０１），且与血浆ＡＶＰ水平呈正相关，与血压无明显相关；降压治疗均恢复正常。ＡＶＰ的下降与尿酸下降呈正相关。提示ＡＶＰ参与低肾素性老年高血压病的发病过程。
hirth-five elderly hypertensive patients of the low renin type were compared with
30matched normotensive control subjects. The venous plasma arginine
vasopressin(AVP)concentrations were significantly increased in the former(P<0.01).AVP
correlated posi-tively with blood pressure. No correlation was found between serum uric acid
and bloodpressure among the hypertensives. The data indicated that AVP plays an important
role inelderly essential hypertensives.The increased serum uric acid most probably results
fromthe increasing tubular reabsorption of the uric acid.
出处
《湖南医科大学学报》
CSCD
1995年第1期52-54,共3页
Bulletin of Hunan Medical University
