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胰岛素样生长因子系统的研究进展 被引量:21

Insulin-like growth factor system and its role in the polycystic ovary syndrome
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摘要 胰岛素样生长因子(IGF)系统由具有特定功能的配体、受体和结合蛋白组成,在胚胎分化和个体发育中有着重要作用,在正常生理活动中也有极为重要的意义。现已发现,许多疾病如糖尿病、胰岛素抵抗、内分泌紊乱、癌症、营养不良和多囊卵巢综合征(PCOS)等与IGF系统密切相关。作者对IGF系统的研究进展进行了阐述。 The insulin-like growth factor (IGF) system is ubiquitous and plays a role in every tissue of the body. There are now numerous examples of diseases such as polycystic ovary syndrome, diabetes, cancer and malnutrition in which the IGF system is a major player.
出处 《医学研究生学报》 CAS 2005年第8期746-750,共5页 Journal of Medical Postgraduates
基金 国家自然科学基金资助项目(批准号:30271353)
关键词 胰岛素样生长因子 受体 结合蛋白 信号通路 多囊卵巢综合征 Insulin-like growth factor Receptor Binding proteins Signaling pathways Polycystic ovary syndrome
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参考文献22

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