摘要
我们检测了89对生育夫妇和128对不育夫妇血清、精浆中抗精浆免疫抑制物抗体(SPI—Ab)的水平。结果表明,不育夫妇血清、精浆SPIM—Ab的水平和检出率均明显高于生育组(P<0.01);精浆SPIM—Ab水平增高者的精子密度、精子活率、精子运动速度和SPIM活性均明显降低(P<0.01)。提示:SPIM—Ab水平增加可能影响生育。
The levels of anti - SPIM antibodies (SPIM -Ab) in serum and seminal plasma were determined in 217 married couples (fertility:89,infertility:128). The resultsshowed that the content and positive rate of serum and seminal plasma SPIM - Ab in the infertile couples were all significantly higher than in the fertile couples (P<0.01).The sperm desity, sperm viability, sperm movement velocity and SPIM activity were decreased evidently (P<0.01),when the level of APIM--Ab in seminal plasma was higher.This study indicated that the elevation of SPIM - Ab level may influence fertility.
关键词
精浆免疫抑制物
精子
抗体
不育症
Seminal plasma inhibition material
Sperm
Antibodies
Infertility