单脐动脉与胎儿畸形（附9例分析）

Single Umbilical Artery and Fetal Ma-Iformation :Analysis of 9 Cases.

我科自１９８９～１９９２年在２３８例胎盘病检中发现单脐动脉９例，发生率３．７８％。单脐动脉胎儿的特点是畸形率高、死亡率高。本组９例中８例胎儿有各类畸形，畸形率达８８．９％。７例胎儿死亡命死亡率７７．８％。本文就单脐动脉的发生率、形成原因及其与胎儿畸形的关系进行讨论，建议加强妊娠早期保健及围产期检查工作。及早发现单脐动脉胎儿，可为诊断先天性畸形或发现一些隐性畸形提供线索，从而指导临床产科处理，有利于优生优育。

rom 1989 to 1992,nine cases of single um-bilical artery were found out of 238 placentasexamined in our department. The incidencewas 3. 78%. The characteristics of fetuseswith single umbilical artery were high mortali-ty and teratogenicity. Eight of these 9 hadvarious kinds of malformation, (88. 9 %) : sev-en were death, (mortality 77. 8%) The inci-dence of single umbilical artery, the cause ofits formation, and its correlation with fetalmalformation are discussed. We consideredthat single umbiliecal artery was an importantfactor to cause fetal malforrnation, but it alsoprobably was one of the congenital malforma-tion which happened at the same time.Whether the fetus with single umbilical arterywas accompanied by malforiliation also relatedto the individual difference of the parturientand environnient. In view of the close relation-ship between single umbilical artery and fetalmalformation,we suggest that the health pro-tection of the first trimester of pregnancy andthe perinatal examination must be strength-ened. In order to instruct the obstericians todiagnoses congenital malformation , or provideleads for some-recessive hereditary malformation in time ,it isnecessary to find out the fetuses with singleumbilical artery as early as possible, and it iswell for aristogenesis.