急性脑出血患者脑脊液及血浆中精氨酸加压素神经降压素和生长抑素含量的变化

Levels of arginine vasopressin , neurotensin and somato-statine in cerebrospinal fluid and plasma of patientswith acute cerebral hemorrhage

测定了２０例急性脑出血患者脑脊液及其中１０例患者血浆中精氨酸加压素（ＡＶＰ）、神经降压素（ＮＴ）和生长抑素（ＳＳ）含量，并与３０例对照组比较。结果：脑出血患者脑脊液及血浆中ＡＶＰ、ＮＴ含量显著增高，脑脊液中ＳＳ含量降低；血浆ＡＶＰ、ＮＴ含量增高，ＳＳ含量无明显变化。提示：ＡＶＰ、ＮＴ及ＳＳ参与了脑出血发病的神经化学机制；ＡＶＰ可能与本病患者脑水肿的发生发展有关。

289 Arginine vasopressin(AVP).neurotensin(NT) andsomatostatine( SS).were measured in the cerebrospinalfluid (CSF ) of the 20 patients with acute cerebral hem-orrhage and in the plasm of the 10 among the above 20patients and in 30 control subjects.The results showedthat the concentrations of AVP and NT in the CSF andplasma of the patients with acute cerebral hemorrhagewere significantly higher and the concentrations of SS inthe CSF were significantly lower than in the controls.Inaddition,plasma AVP and NT were increased , but plas-ma SS was not found to have any significant change, Ourstudy indicated that AVP,NT and SS participated in theneurochemical mechanism in cerebral hemorrhage attackand AVP might be related to the emergence and evolu-tion of cerebral edema in patients with acute cerebralhemorrhage.