摘要
粉防己碱(Tet)和牛磺酸(Tau)均能抑制ADP、胶原和凝血酶诱导的大鼠血小板聚集及血栓形成。Tet抑制ADP诱导聚集较强,Tau则对胶原作用最明显,二药减半量合并应用时。
The effects of tetrandine (Tet), Taurine(Tau) and Tet+Tau on platelet aggregation and thrombosis were studied in rat. Tet and Tau inhibited rat platelet aggregation induced by ADP, collagen and thrombin. Bothdrugs reduced wet weight of experimental thromb and the effeets of Tet+Tau were markedly increased.Which suggested that the effects of the drug combination were more potental than the single administration.
出处
《中国药理学通报》
CAS
CSCD
北大核心
1995年第5期398-402,共5页
Chinese Pharmacological Bulletin