雷贝拉唑联合左氧氟沙星和呋喃唑酮根除胃幽门螺杆菌的疗效观察

Observation on effects of the union of rebeprazole,levofloxacin and furazolidone in eradication of Helicobecter pylori

目的观察雷贝拉唑联合左氧氟沙星和呋喃唑酮根除胃幽门螺杆菌的疗效。方法治疗组用雷贝拉唑联合左氧氟沙星和呋喃唑酮根除胃幽门螺杆菌(HP),并与对照组雷贝拉唑联合阿莫西林和克拉霉素治疗幽门螺杆菌(HP)相比较。结果治疗组在症状缓解、溃疡愈合、不良反应等方面与对照组差异无统计学意义(P>0.05),在HP感染根除率方面治疗组优于对照组(P<0.05)。结论以雷贝拉唑为中心的联合左氧氟沙星、呋喃唑酮组成的新三联是一种高效安全的治疗消化性溃疡和根除HP感染的方案,值得推广。

Objective To observe the effects of the union of rebeprazole,levofloxacin and furazolidone in eradication of Helicobecter pylori.Methods The treatment group which was treated with rebeprazole,levofloxacin and furazolidone in eradication of Helicobecter pylori was compared with the control group which was treated with the union of rebeprazole,amoxicillin and clarithromycin.Results There was no difference in symptom relief,ulcer healing and adverse reaction between the treatment group and the control group(P>0.05).However,the rate of eradication of Helicobecter pylori was decreased in the treatment group compared to the control group(P<0.05).Conclusion in the center for Bella thiazole joint levofloxacin,furan was composed of new sanlian is an effective and safe treatment of peptic ulcer and eradicate HP infection,is worthy to be popularized.