脑血栓片质量标准研究

Study on Quality Standard for Naoxueshuan Tablets

目的:建立脑血栓片的质量标准;方法:采用薄层色谱法(TLC)对该片中丹参、川芎和赤芍等有效成份进行定性鉴别;采用高效液相色谱法测定芍药苷的含量;结果:TLC色谱中均能明显地检出丹参、川芎和赤芍;芍药苷含量测定线性范围 0．4～2．4 μg,r=0．999 9,平均回收率99．97％,RSD=1．32％(n=5);结论:该检测方法准确可靠,可用于该制剂的质量控制。

Objective： To establish the quality standard for Naoxueshuan tablets. Method： Radix salvia miltiorrhiza, Rhizoma chuanxiong and Radix Paeoniae Rubra were identified by TLC. The content of paeoniflorin was determined by HPLC. Result： Radix salvia mihiorrhiza, Rhizoma chuanxiong and Radix Paeoniae Rubra could be detected by TLC. The paeoniflorin showed a good linear correlation in the range of 0.4-2.4 μg（ r = 0. 999 9）. The average recovery was 99.97% （RSD = 1.32% ）. Conclusion： The method is convenient and accurate. It is suitable for quality control of Naoxueshuan tablets.