摘要
自1980年4月至1995年9月,采用胸腺切除治疗重症肌无力34例。年龄5~62岁。术后早期死亡1例,死亡率2.94%。33例随访3个月至12年。1年内缓解和改善率为87.9%(29/33),1~3年缓解和改善率为88.5%(23/26),3年以上缓解和改善率为80.0%(4/5)。随访结果表明胸腺切除治疗重症肌无力效果满意。延迟拔除气管插管或早期行气管切开术,是防治术后重症肌无力危象的有效措施。胸腺肿瘤已侵及包膜或有局限性恶变的患者术后放疗可以减少复发率,延长生存时间。
From April 1980 to September 1995,34 patients with myasthenia gravis (MG) underwent thymeetomy.The ages ranged from 3 to 64 years.Pathologic diagnosis for thymus were: thymoma in 19 cases with malignant chang in 8,hy perplasia in 12,no abnormality found in 3.Postoperatively, 1 patient died in the hospital,the early postoperative death rate was 2.94% (1/34).Thirty-three cases were followed up from 3 months to 12 years.The result showed: total remission and improvement rate in 1 year was 87.9% (29/ 33),in 1~3years was 88.5% (23/26),over 5 years was 80% (4/5).The authors consider that thymectomy is an ef- fective treatment for MG.Early tracheostomy .or prolonged trachea cannulation for severe MG after thymectomy is very important for preventing postoperative respiratory failure. Postoperative radiation can reduce the recurrence rate.
出处
《中国胸心血管外科临床杂志》
CAS
1996年第1期22-23,共2页
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery