摘要
我们应用巴曲酶治疗缺血性脑血管病时,曾发现该药能迅速控制频发的短暂脑缺血发作(TIAs)。本文目的是通过多中心随机、对照(与传统常规用药)研究,观察该药是否确实能速控频发TIAs。总数为55例患者,根据TIAs患者的性别、年龄、严重程度,将患者随机分为巴曲酶治疗组及传统常规治疗组。入院后进行神经系统检查;并即予以治疗,观察及记录其发作终止之时间。结果为巴曲酶组有68.97%病人在3日内发作控制,而对照组仅19.23%,差异非常显著(X2=13.921,P<0.01)。表明巴曲酶确能迅速控制频发的TIA。
We have found that batroxobin could rapidly control transient ischemid with frequent attacks (TIAs).The present study was a randomixed,tradition-treatment-controlled, multicenter trial which was conducted to test and reconfirm whether batroxobin could stop TIAs rapidly.A total of 55 patients were randomized to batroxobin or matching tradition-treatment for 28 days. Randomization was stratified by age,sex and TIAs seventy.The patient had neurological evaluation on admission and treatment was begun immediately after admission. The time for stopping TIAs was recorded.We found that in batroxobin-treated group 68.97% of patients were free from attacks with in 3 days after.treatment,while in tradition - treatment group, only 19.23% of patients.There was a significant difference between the batroxobin -treated and tradition -treated groups(X2=13.921, P<0.01).The results indicate that batroxobin can rapidly stop TIAs.
出处
《脑与神经疾病杂志》
1996年第2期65-70,共6页
Journal of Brain and Nervous Diseases
关键词
脑缺血发作
巴曲酶
药物疗法
TIA with frequent attacks Batroxobin Randomized,controlled,multicenter study