摘要
我们对600例停经42天内的早孕妇女分两组分别应用米非司酮联合紫草配伍米索前列醇及米非司酮配伍米索前列醇进行药物流产,结果表明米非司酮联合紫草组的完全流产率(99.00%)明显高于米非司酮组(92.33%)(P<0.01).前者用米非司酮和紫草后孕囊排出时间(54.01±7.55小时)及服用米索前列醇后6小时内的孕囊排出率(82.33%)较后者(56.41±9.93小时、72.67%)明显缩短和升高(P均小于0.05),且出血时间(7.01±3.11天)和出血时间超过10天的发生率(12.46%)亦较后者(8.09±5.63天,24.91%)明显缩短和减少(P值分别小于0.05和0.01).两组流产后月经转复天数无明显差别(P>0.05).由此可见,紫草可提高米非司酮药物流产的成功率、缩短出血时间,因此有必要对其提高药物流产效果的作用进行进一步的探讨.
Early pregnancies (≤ 42days ) in 600 women were terminated respectively by mifepristone Zhichao with misoprostol and mifepristone with misoprostol. The results showed that the rate of complete abortion (99. 00%) of 300 women by mifepristone-Zhichao with misoprostol was significantly higher than that (92. 33%) of 300 women by mifepristone with misoprostol (P<0. 01).The average length of time of embryo removal (54. 01±7. 55 h) and the rate of embryo removal (82. 33%) within 6 hours after using misoprostol in the former were both significantly shorter and higher than those(56. 41±9. 93 and 72. 67%) in the latter(P<0. 05 respectively). The average length of the bleeding time of the former (7. 01±3. 11 d) was significantly shorter than that of the latter (8. 09±5. 63 d) (P<0. 05). The recovery of the menstruation of both was not significantly different(P>0. 05). As a result, the medical abortion by mifepristone -Zhichao with misoprostol was even more successful,remarkably reducing time of bleeding. So it is essential to make researches on the auxiliary effects of Zhichao on the medical abortion with mifepristone and misoprostol.
出处
《生殖与避孕》
CAS
CSCD
北大核心
1996年第3期199-202,共4页
Reproduction and Contraception