2003年泰安市部分手足口病住院病例分析

Analysis of Inpatients with Hand Foot and Mouth Disease in Tai'an Area in 2003

[目的]了解手足口病发病情况、临床特征.[方法]对泰安市中心医院等8家重点医院2003年4～9月收治的泰安市手足口病住院病例723例进行调查.[结果]723例中,男性454例、女性269例;单纯手足口病429例,合并心肌炎191例、脑炎85例、脑心肌炎18例;死亡2例;病人分布在7个县(市、区、矿业集团)的65个乡镇矿,其中新泰市512例.7月、8月为发病高峰.体温39℃以上病例占54.77%.检测急性期病人粪便、咽拭子110份,病毒分离阳性50份,其中包括COX16、ECHO19、EV71等3种7型病毒;检测急性期、恢复期病人血清107份,手足口病相关抗体阳性27份.[结论]泰安市2003年发生了手足口病流行,其病原以ECHO19为主.

[Objective]To find out epidemiological and clinical characteristics of hand foot and mouth disease（HFMD） in Tai＇an area in 2003. [Methods]Investigating 723 inpatients with HFMD from 8 hospitals,such as the Center Hospital of Tai＇an,in April to SeW tember in 2003. [Results]723 cases of HFMD,including 454 male and 269 female; 429 cases were simple HFMD,430 myocarditis,85 encephalitis, 18 both encephalitis and myocarditis, 2 cases died; All cases distributed in 7 counties（districts,mining areas）, 65 townships（mining areas） ,512 cases were in Xintai area among them. Most patients were in July to August. 54.77% cases had a fever higher than 39℃. Tested 110 specimens of stool and thoat swabs from patiens in acute period, 50 were isolated viruses,and CoxA16, Echo19 and Ev71 with 3 kinds and 7 serotypes were confirmed; Tesfing 107 serm specimens from patiens in acute and recovery period,and 27 were isolated related-antibodies of HFMD. [Conclusion]A prevalence of HFMD occurred in Taian area in 2003 with the first pathogen being Echo19.