10～11岁农村儿童幽门螺杆菌感染研究分析

Studies on Helicobaeter Pylori Infected Situation in Country Children Aged 10～11Years Old

目的了解我国农村10～11岁儿童幽门螺杆菌(Hp)感染率,有反复腹痛史和父母有胃病史儿童与正常儿童幽门螺杆菌(Hp)感染率的差异.方法采用14C-尿素呼气试验(14C-UBT)检测119例农村儿童,其中有反复腹痛史40例;无反复腹痛史79例;父母有胃病史儿童48例,父母无胃病史71例.结果儿童Hp感染率为46.2%,无反复腹痛史儿童Hp感染率为36.7%,有反复腹痛史儿童Hp感染率为65.0%.119例儿童中父母有胃病史的儿童Hp感染率为60.4%,父母无胃病史儿童Hp感染率为36.6%.男童Hp阳性29例,感染率为24.3%,女童Hp阳性26例,感染率为21.8%.结论我国农村儿童Hp感染阳性率较其他发展中国家低.儿童的反复腹痛史同Hp感染有关,父母中有胃病史同儿童Hp感染有关,说明幽门螺杆菌可能在家庭成员间传播.对有胃病的父母进一步做胃镜检查或进行清除Hp治疗,是否可以减少儿童通过家庭成员感染Hp还有待研究.

Objective To investigate the helicobacter pylori （Hp） infected rate in Chinese country children and the difference of Hp infected rate between normal children and children with repeatedly abdominalgla history or which parents have gastropathy history. Methods The Hp infected situation in 119 country children were determined by^14C -Urea Breath Test （C -UBT）. In 119 children, 40 have repeatedly abdominalgia history, while 79 have no repeatedly abdominalgia history. 48 chil- dren＇s parents have gastropathy history while 71 children＇s parents have no gastropathy history. Results The average infected rate in all the children was 46. 2% , while it was 65.0% and 36. 7% in children with or without repeatedly abdominalgia history, 60. 4% and 36. 6% in children whose parents have or have no gastropathy history. Conclusion The average infected rate of hp is lower in Chinese country children than that in other developed country. There is a significant possible correlation between children, repeatedly abdominagia history and Hp infected rate. There is also a significant positive correlation between children＇s parent gastropathy history and Hp infected rate, which indicates that hp may communicate among family members. The probabilities of children infected Hp from family members whether can be decreased by giving their parents gastroscopy or Hp eliminated therapy need to be further studied.