免疫佐剂作用机理的研究进展

Updated advances in mechanisms of adjuvants

随着DNA重组疫苗、合成肽疫苗等新型疫苗不断涌现,免疫佐剂研究越来越受到人们的关注。尽管佐剂活性物质的研究报道很多,但由于佐剂加强免疫反应是一个非常复杂的过程,关于各种佐剂的作用机制至今尚未完全了解。本文对近年来免疫佐剂作用机理研究进展作一综述,为促进免疫佐剂作用机理的深入研究及免疫佐剂的合理应用提供参考,并初步探讨其作用机理研究的重要性及意义。

With the development of vaccines, such as recombinant DNA vaccines and synthetic peptide vaccines, the studies on adjuvant become more interested. While the number of substances with adjuvant activity and the literature describing their use has expanded enormously, their mechanism has remained largely mysterious. This review represents the developments in the study on adjutant＇s mechanisms, discusses the importance of the study on mechanisms, trends of. All these could provide some conferences for the further study on adjutant＇ s mechanisms and reasonable usage of the adjuvants.