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子宫NK细胞与妊娠关系的研究 被引量：3

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摘要 子宫NK(uNK)细胞是妊娠子宫最主要的淋巴细胞,它参与了母胎界面免疫平衡的维持。本文简要介绍了uNK细胞的来源、分化和分布特征,重点论述了uNK细胞受体库的组成、功能以及与妊娠的关系。
作者 赵丽丽 曲迅 孔北华
机构地区 [ 山东大学齐鲁医院临床基础研究所 山东大学齐鲁医院妇产科
出处 《国外医学（免疫学分册）》 2005年第6期346-350,共5页 Foreign Medical Sciences(Section of Immunology Foreign Medical Sciences)
关键词 子宫NK细胞 妊娠 受体库
分类号 R392.1 [医药卫生—免疫学]
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参考文献20

  • 1Bulmer JN,Lash GE.Human uterine natural killer cells:a reappraisal[J].Mol Immunol.2005,42(4):511-521.
  • 2Barber EM,Pollard JW.The uterine NK cell population requires IL-15 but these cells are not required for pregnancy nor the resolution of a Listeria monocytogenes infection[J].J Immunol,2003,171(1):37-46.
  • 3Chantakru S,Miller C,Roach LE,et al.Contributions from self-renewal and trafficking to the uterine NK cell population of early pregnancy[J].J Immunol,2002,168(1):22-28.
  • 4Croy BA,Esadeg S,Chantakru S,et al.Update on pathways regulating the activation of uterine Natural Killer cells,their interactions with decidual spiral arteries and homing of their precursors to the uterus[J].J Reprod Immunol,2003,59(2):175-191.
  • 5Verma S,Hiby SE,Loke YW,et al.Human decidual natural killer cells express the receptor for and respond to the cytokine interleukin 15[J].Biol Reprod,2000,62(4):959-968.
  • 6Okada H,Nakajima T,Sanezumi M,et al.Progesterone enhances interleukin-15 production in human endometrial stromal cells in vitro[J].J Clin Endocrinol Metab,2000,85(12):4765-4770.
  • 7Gubbay O,Critchley HO,Bowen JM,et al.Prolactin induces ERK phosphorylation in epithelial and CD56(+) natural killer cells of the human endometrium[J].J Clin Endocrinol Metab,2002,87(5):2329-2335.
  • 8Henderson TA,Saunders PT,Moffett-King A,et al.Steroid receptor expression in uterine natural killer cells [J].J Clin Endocrinol Metab,2003,88(1):440-449.
  • 9Moffett-King A.Natural killer cells and pregnancy[J].Nat Rev Immunol,2002,2(9):656-663.
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同被引文献39

  • 1赵丽丽,曲迅,梁璐,杨美香,董白桦,吕晓梅,孔北华.妊娠早期子宫微环境中蜕膜、滋养层及子宫NK细胞基因表达的研究[J].中华微生物学和免疫学杂志,2006,26(1):60-64. 被引量：5
  • 2王春,许灿新,彭翠英,秦旭平,李凯,廖端芳.M-CSF促进RAW 264.7细胞MMP-9的分泌及其可能机制[J].中国药理学通报,2006,22(8):947-951. 被引量：6
  • 3Wang H, Dey S K. Roadmap to embryo implantation: clues from mouse models[J]. Nat Rev Genet,2006;7(3) : 185-199.
  • 4Zhang Y, Peng S, Kuang H B et al. Expression and regulation of Dickkopf2 during periimplantation in mice[J]. J Reprod Dev, 2009; 55( 1 ) : 17-22.
  • 5Yang Y J, Liu W M, Zhou J X et al. Expression and hormonal regulation of calcyclin-binding protein (CacyBP) in the mouse uterus during early pregnancy [ J ]. Life Sci, 2006; 78 (7) : 753-760.
  • 6Herington J L, Bany B M. Effect of the conceptus on uterine natural killer cell numbers and function in the mouse uterus during decidualization[J]. Biol Reprod, 2007 ; 76(4) : 579-588.
  • 7Paffaro VA Jr, Bizinotto M C, Joazeiro P P et al. Subset classification of mouse uterine natural killer cells by DBA lectin reactivity [ J ]. Placenta, 2003 ; 24( 5 ) :479-488.
  • 8Stewart I,Peel S. Granulated metrial gland cells in the virgin and early pregnant mouse uterus[J]. J Anat, 1981 ; 133(Pt4) :535-541.
  • 9Bilinskil M J, Thomel J G, Oh M Jet al. Uterine NK cells in murine pregnaney [ J ]. Reprod Biomed Online, 2008 ; 16 (2) : 218-226.
  • 10Okada H, Nakajima T, Sanezumi Met al. Progesterone enhances interleukin-15 production in human endometrial stromal cells in vitro [ J]. J Clin Endocrinol Metab, 2000; 85 ( 12 ) : 4765-4770.

引证文献3

二级引证文献7

国外医学（免疫学分册）
2005年 第6期

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