摘要
目的:研究白鲜Dictamnus dasycarpus干燥根皮的化学成分。方法:采用硅胶柱色谱、制备薄层色谱、Sephadex LH-20等方法分离,应用波谱方法鉴定其结构。结果:从白鲜皮中分离得到12个化合物,分别为白鲜碱(dictamnine,Ⅰ),酮(fraxinellone,Ⅱ),茵芋碱(skimmianine,Ⅲ),γ-崖椒碱(-γfagarine,Ⅳ),β-谷甾醇(-βsitosterol,Ⅴ),黄柏酮(obacunone,Ⅵ),柠檬苦素地噢酚(limonin disophenol,Ⅶ),fraxinellonone(Ⅷ),汉黄芩素(wogonin,Ⅸ),如忒文(rutevin,Ⅹ),kihadinin B(Ⅺ),dasycarine(Ⅻ)。结论:化合物Ⅸ,Ⅺ为首次从该属植物中分离得到,化合物Ⅷ为首次从本植物中分离得到。
Objective: To study the chemical constituents in bark of Dictamnus dasycarpus. Method: Isolation and purification were carried out on silica gel column chromatography, prepared thin layer chromatography and sephadex LH - 20, et al. The structures were identified by spectral analysis. Result: Twevle compounds were obtained from bark of D. dasycarpus and the structures were determined as dictamnine (Ⅰ), fraxinellone (Ⅲ) , skimmianine ( m ),γ-fagarine (Ⅳ), β-sitosterol (Ⅴ ), obacunone ( Ⅵ ), limonin disophenol (Ⅶ), fraxinellonone (Ⅷ), wogonin (Ⅸ), rutevin (Ⅹ), kihadinin B ( Ⅺ), dasycarine (Ⅻ). Conclusion: Compounds Ⅸ and Ⅺ were isolated from genus Dictamnus for the first time, and compound Ⅷ was isolated from the species for the first time.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2005年第21期1663-1666,共4页
China Journal of Chinese Materia Medica
基金
国家"九五"重点科技攻关计划项目基金(99-929-01-25)
关键词
白鲜
芸香科
生物碱
柠檬苦素
Dictamnus dascarpus
Rutaceae
alkloids
limonoids