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湖南汉族MICA*008/A5.1等位基因的调查分析

Investigation of MICA*008/A5.1 Allele in Hunan Han Nationality
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摘要 目的调查湖南汉族群体MICA008/A5.1等位基因的频率分布。方法应用PCR/SSP技术对81名无血缘关系的湖南汉族健康个体作MICA008/A5.1等位基因检测。结果检测出MICA008/A5.1等位基因的频率为56.8%。结论湖南汉族群体MICA008/A5.1等位基因频率较高,并提供了湖南汉族群体MICA008/A5.1等位基因频率的正常参考值。 Objective To investigate the frequency of MICA * 008/A 5.1 allele in Hunan Han nationality. Method Eighty- one samples randomly selected from healthy individuals of Han nationality in Hunan Province and the MICA * 008/A 5.1 allele were detected by POR/SSP assay. Results 56.8% MICA * 008/A5.1 allele was found in all 81 samples. Conclusions The MICA * 008/A5.1 allele frequency is significantly higher in Hunan Han nationality. At the same time, normal reference value of MICA * 008/A5.1 allele of Hunan Han nationality is provided.
出处 《实用预防医学》 CAS 2005年第3期509-510,共2页 Practical Preventive Medicine
关键词 湖南汉族 MICA基因 等位基因 Han nationality in Hunan Province MICA gene Allele
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  • 1Bahram S, MIC genes, from genetics to biology[J ]. Adv Immunol,2000,76: 1 - 60.
  • 2Bahram S, Bresnahan M, Geraghty DE, et al. A second line age of mammalian major histocompatibility complex class I genes[J]. Proc. Natl.Acad. Sci, 1994,91:6259-63.
  • 3Visser CJ, MG Tilanus, Z Tatari, et al. Sequencing -based typing of MICA reveal 33 alleles: a study on linkage with classical HLA genes [J]. Immunogenetics, 1999,49: 561.
  • 4Zhang Y, AM Lazaro, B Lavingia,et al. Typing for all known MICA is a alleles by group-specific PCR and SSOP[J]. Hum lmmunol, 2001,62:620.
  • 5Katsuyama Y. Ota M, Ando H, et al. Sequencing based typing for genetic polymorphisms in exons, 2, 3 and 4 of the MICA gene[J ]. Tissue Antigens, 1999,54(2): 178 - 84.
  • 6Ota M, Katsuyama Y, Mizuki N, et al. Trinucleoti-de repeat poly morphism within exon 5 of the MICA gene (MHC class I chain- related gene A): allele frequency data in the nine population groups Japanese, Northern Han, Hui, Uygur, Kazakhstan, Iranian, Saudi Arabian, Greek and Italian [J]. Tissue Antigens, 1997,49: 448 - 54.
  • 7龚卫娟,范丽安,杨珏琴,许玲娣,姚芳娟.三个群体MICA基因外显子2、3和4的多态性研究[J].中华医学遗传学杂志,2002,19(4):336-339. 被引量:17
  • 8班贵宏,褚嘉祐,许绍斌,杨昭庆,钱亚屏,俞建昆,纳剑波,刘晓娟,张思仲.MICA基因微卫星多态在中国13个群体中的分布[J].Acta Genetica Sinica,2001,28(12):1085-1092. 被引量:6

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