几种不同治疗手段对原发性肝癌的疗效比较研究

Efficacy of different therapies for hepatocellular carcinoma

目的对原发性肝癌儿种不同治疗手段疗效进行比较分析,为临床合理化治疗方案的确定提供参考与帮助。方法我院1999年6月至2003年6月收治原发性肝癌病例中80例分为A组:单纯手术组;B组:手术切除+植入式肝动脉化疗泵化疗组;C组:单纯肿瘤内注射无水酒精组;D组:股动脉穿刺介入治疗组。对不同治疗手段疗效进行比较分析。结果治疗后A、B、C、D四组1年生存率分别为60.13%、71.26%、43.15%、42.78%,2年生存率分别为46.52%、51.38%,26.64%,25.83%。A、B组术后1年复发率分别为60.33%,49.28%,术后2年复发率分别为76.59%,61.24%。结论对原发性肝癌的治疗以手术切除病灶加化疗的综合治疗效果最佳,单纯手术切除较荷瘤的其他治疗手段效果好,但对无法手术切除的病例肿瘤局部用药的治疗手段仍具有一定的控制效果。

Objective Study on the curative effects of different therapies for hepatoeellular carcinoma. Methods Analyzing the clinical data of 80 patients with primary hepatocellular carcinolna from June 1999 to June 2003. The patients were divided into four groups. Croup A was twenty patients with hepatoectomy, group B was twenty patients with hepatectomy colnbining implantable drug delivery system; group C was twenty patients with the ethanol injecttion into liver carcinomas, group D was twenty patients who had the chemotherapy from the femoral artery, Results The one year survival rates of the four groups were 60,13% , 71.26% , 43,15% and 42.78% respectively, The two years＇ survival rates of the four groups were 46.52%, 51.38%, 26.64% and 25.83% respectively. The postoperative recurrent rates of group A and B were 60.33%, 49.28% for one year and 76.59%, 61.24% for two years, Conclusion For primary hepatocel lular carcinoma, hepatectomy combining chemotherapy is the most helpful method, The tumor excision method is better than other methods which had the tumors unresected,