摘要
目的探讨通心络胶囊对肺心病急性加重期患者血液流变学及高疑状态的影响。方法将80例肺心病急性加重期病人随机分为两组,对照组给予常规治疗,治疗组在常规治疗基础上加通心络胶囊治疗,4周为1疗程。观察两组治疗前后血液流变学、血浆D-D聚体、血红蛋白、红细胞压积的变化,并评价其疗效。结果治疗组总有效率为95%,对照组为70%,两组比较,差异有统计学意义(P<0.01);治疗组血液流变学、血浆D-D聚体、血红蛋白及红细胞比治疗前与对照均有明显变化(P<0.05或P<0.01)。结论通心络治疗肺心病急性加重期疗效显著,明显改善患者血液流变学,降低D-D聚体、血红蛋白、红细胞压积,改善患者预后。
Objective To investigate the effects of Tongxinluo capsule on hemorheology and hypercoagulable state in patients with acute exacerbations of pulmonary heart disease. Methods Eighty patients with acute exacerbations of pulmonary heart disease were randomly divided into control group or therapeutic group. The control group was given conventional therapy and the therapeutic group was given Tongxinluo capsule for 4 weeks in addition to the conventional therapy. The therapeutic effects were evaluated by changes of hemorheology, D-dimer, haemoglobin and hematocrit in the two groups. Results The total effective rates in therapeutic group and control group were 95% and 70%, with a significant difference between the two groups （P〈0. 01）. Hemorheology, D-dimer, haemoglobin and hematocrit were significantly improved in the therapeutic group than pretreatment and control group （P〈0. 05 or P〈0.01）. Conclusion Tongxinluo capsule is effective and can ameliorate prognosis for patients with acute exacerbations of pulmonary heart disease.
出处
《西部医学》
2006年第1期24-25,共2页
Medical Journal of West China
