摘要
目的研究胆囊运动功能与胆结石形成的关系。方法 1991-1992年用核素显像方法测定了正常人和胆结石患者的胆囊充盈和排空率。静注99mTC-EHIDA 185MBq 60 min 时(此时胆囊已满意充盈),给予标准混合试餐。以后用Technicare Sigma-438型γ像机采集肝胆动态像。比较30例正常人和40例胆结石患者10,30和60min 的胆囊排空率(GER)。结果胆结石患者 GER(30及60min)明显低于正常,且多发结石较单发结石为低。正常同年龄女性较男性为低,与女性患胆石症比例增高相一致。其中多次妊娠妇女更易罹患。其余因素如年龄、体型(重)等则未发现相关。结论试餐法测定胆囊运动功能适合临床应用。此测定可能对胆结石成因的研究和非手术疗法的实施有一定作用。
AIMS To understand the motility function of gallbladder, the gallbladder emptying rate(GER)of normal subjects and cholelithiasis patients were performed. METHODS Gallbladder filling and emptying induced by mixed standard test meal were quantitied by computer-assisted cho- lescintigraphy in 30 normal subjects and 83 patients with gallstones. RESULTS GB emptying rate in gallstone patients(62.8%± 26.4%)at 60 min was significantly reduced(P<0.01)com- pared with that of the controls(81.6%±13.1%). CONCLUSIONS Impaired emptying of gallbladders would be considered in pathogenesis of gallstone or in medical therapy in these patients.
关键词
胆结石
胆囊排空率
胆囊运动功能
cholelithiasis
choleeystography
gallbladder emptying rate