原发性骶前肿瘤147例临床病理分析

Clinical analysis of primary presacral tumors: a report of 147 cases

回顾性分析1954～2004年收治的147例原发性骶前肿瘤患者的临床病理资料,结果显示,原发性骶前肿瘤的主要诊断方法包括直肠指诊、B超和CT检查;肿瘤病理类型复杂,147例共涉及不同病理类型30种,其中良、恶性分别为49.7%和50.3%;主要治疗手段为手术治疗,本组病例肿瘤完整切除者77例,部分切除者32例,二次手术者18例;78例骶前恶性肿瘤联合应用放、化疗或免疫治疗,综合治疗的疗效与原发肿瘤的组织学类型、肿瘤体积等因素有关;患者生存期3个月～14年,中位生存期2年,影响预后的主要因素为肿瘤的组织学类型、肿瘤的手术切除率及综合治疗的应用。

The objective of this study was to analyse retrospectively the clinical and pathologival data of 147 patients with primary presacral tumor from 1954 to 2004. The results showed; that the main diagnosis approaches of the primary presacral tumors were anoscopy, ultrasonography （USG） and computed tomographic（CT）. The pathological types of primary presacral tumors were complex. As to the data, there were 30 different pathological types revolved, and among them, 49.7% were benign and 50. 3% malignant respectively. The main therapy was surgical resection. In the data, the tumor was completely resected in 77 cases; partially resected in 32 cases; secondary operation was completed in 18 cases. A total of 78 cases were treated by surgery combined with radiotherapy, chemotherapy or immunotherapy. The effect of integrative therapy was depended on the histological type, the volume of the tumor and so on. The life span of the patients were from 3 months to 14 years and the median survival term was 2 years. The main influencing factors were the histological type, the resected rate of the tumor, the application of integrative therapy.