清胰汤在重急性胰腺炎治疗中的作用

The use on curative effect of Chinese medicine Qingyitang in severe acute pancreatitis

目的观察中药清胰汤治疗重症急性胰腺炎(SAP)的临床疗效。方法132例SAP患者随机分为治疗组(70例)和对照组(62例),两组均给予常规治疗,治疗组加用清胰汤,每日1剂,分4次从胃管注入。分别观察两组患者平均腹胀消退时间、平均禁食时间、平均住院时间、手术率、胰周感染率并进行比较。结果治疗组的各项观察指标明显优于对照组(t检验,P<0.05)。结论中药清胰汤能明显促进胃肠道功能恢复,减少肠道细菌移位,减轻急性炎症反应综合征,减轻胰腺损害,促进胰腺修复,提高疗效,缩短疗程。

Objective To study the use on curative effect of Chinese medicine Qingyitang in severe acute pancreatitis. Methods 132 cases of severe acute pancreatitis were randomly divided into 2 groups,The control group （n = 62） and the treatment group（ n=70）. Routine treatment were given in both,otherwise, the Chinese medicine Qingyitang was used in the treatment group. The operation rate,the infection rate, the time of abdominal distension removing and fasting and being hospitalized were observed and compared between two groups. Results Every index of the treatment group was finer than the control group. Conclusions The Chinese medicine Qingyitang showes their protective effects on gut barrier function by alleviating the damage of intestinal mucosa and microecologic disturbance following acute pancreatitis. As a result,the chances of bacterial translocation and enterogenic infection declines. These preparation might raise the treatment effects, as a well, shorten the course of treatment.